Article
An evaluation of single nucleotide polymorphisms in the human aryl hydrocarbon receptor-interacting protein (AIP) gene.
Drug metabolism and pharmacokinetics - 1 Jan 2011
Rowlands J Craig, Urban Jonathan D, Wikoff Daniele Staskal, Budinsky Robert A
Abstract excerpt
The human aryl hydrocarbon receptor (AHR) is a protein for which there is little evidence of polymorphic variability of functional consequence. It has been hypothesized that potential variability in dioxin sensitivity may be due to polymorphisms in AHR-associated proteins, such as the human AHR-interacting protein (AIP). There are limited data on AIP single nucleotide polymorphisms (SNPs) with potential...
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