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Article

The human AHR: identification of single nucleotide polymorphisms from six ethnic populations.

Pharmacogenetics and genomics - 1 May 2010

Rowlands J Craig, Rowlands Craig J, Staskal Daniele F, Gollapudi Bhaskar, Budinsky Robert

Abstract excerpt

BACKGROUND: The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related dioxin-like chemicals are mediated through binding-dependent activation of the cytosolic aryl hydrocarbon receptor (AHR). The human AHR is a low-affinity receptor relative to most rodents, but some reports suggest that there may be individuals with polymorphic high-affinity receptors, thereby possibly increasing the sensitivity to dioxins...

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Source

Identifiers

PMID: 20401977
DOI: 10.1097/fpc.0b013e32833605f8

Genes

AHR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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