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Article

Combined sequence and sequence-structure-based methods for analyzing RAAS gene SNPs: a computational approach.

Journal of receptor and signal transduction research - 1 Dec 2014

Singh Kh Dhanachandra, Karthikeyan Muthusamy

Abstract excerpt

The renin-angiotensin-aldosterone system (RAAS) plays a key role in the regulation of blood pressure (BP). Mutations on the genes that encode components of the RAAS have played a significant role in genetic susceptibility to hypertension and have been intensively scrutinized. The identification of such probably causal mutations not only provides insight into the RAAS but may also serve as antihypertensive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24878201
DOI: 10.3109/10799893.2014.922575

Genes

ACE
AGT
CMA1
REN

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