Article
Genetic variations of the AHR gene encoding aryl hydrocarbon receptor in a Japanese population.
Drug metabolism and pharmacokinetics - 1 Aug 2004
Fukushima-Uesaka Hiromi, Sai Kimie, Maekawa Keiko, Koyano Satoru, Kaniwa Nahoko, Ozawa Shogo, Kawamoto Manabu, Kamatani Naoyuki, Komamura Kazuo, Kamakura Shiro, Kitakaze Masafumi, Tomoike Hitonobu, Ueno Kazuyuki, Minami Hironobu, Ohtsu Atsushi, Shirao Kuniaki, Yoshida Teruhiko, Saijo Nagahiro, Saito Yoshiro, Sawada Jun-ichi
Abstract excerpt
Aryl hydrocarbon receptor (AhR), encoded by the AHR gene, is a transcriptional factor that induces various drug metabolizing enzymes in response to diverse endogenous and exogenous ligands. In order to identify genetic variations of the AHR gene, genomic DNA from 242 Japanese individuals was sequ...
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