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Article

GATA6 regulates aging of human mesenchymal stem/stromal cells

30 Nov 2020

Abstract excerpt

Cellular reprogramming forcing the expression of pluripotency markers can reverse aging of cells, but how molecular mechanisms through which reprogrammed cells alter aging-related cellular activities still remains largely unclear. In this study, we reprogrammed human synovial fluid-derived mesenchymal stem cells (MSCs) into induced pluripotent stem cells (iPSCs) using six reprogramming factors and reverted the...

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PMID: 33252174
DOI: 10.1002/stem.3297

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