Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Growth differentiation factor 6 derived from mesenchymal stem/stromal cells reduces age-related functional deterioration in multiple tissues

14 Jun 2016

Abstract excerpt

The senescence-associated secretory phenotype (SASP) has attracted attention as a mechanism that connects cellular senescence to tissue dysfunction, and specific SASP factors have been identified as systemic pro-aging factors. However, little is known about the age-dependent changes in the secretory properties of stem cells. Young, but not old, mesenchymal stem/stromal cells (MSCs) are a well-known source of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mesenchymal stem cell research
Share to MicroRNA in disease regulation
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27311402
DOI: 10.18632/aging.100982

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Growth differentiation factor 6 derived from mesenchymal stem/stromal cells reduces age-related functional deterioration in multiple tissuesPMID 27311402Read ↗

Growth differentiation factor 11: a “rejuvenation factor” involved in regulation of age-related diseases?Semantic proximity Read ↗

Rejuvenation of Mesenchymal Stem Cells to Ameliorate Skeletal AgingSemantic proximity Read ↗

Insulin-like growth factor binding proteins 4 and 7 released by senescent cells promote premature senescence in mesenchymal stem cellsSemantic proximity Read ↗

Isolation of a Stable Subpopulation of Mobilized Dental Pulp Stem Cells (MDPSCs) with High Proliferation, Migration, and Regeneration Potential Is Independent of AgeSemantic proximity Read ↗

Molecular Mechanisms Contributing to Mesenchymal Stromal Cell AgingSemantic proximity Read ↗

GATA6 regulates aging of human mesenchymal stem/stromal cellsSemantic proximity Read ↗

Secretome of Young Mesenchymal Stromal Cells Rejuvenates Aged Mesenchymal Stromal Cells by Normalizing Their Phenotype and Restoring Their Differentiation Profile.Semantic proximity Read ↗

Mesenchymal stem cells: A revolution in therapeutic strategies of age-related diseasesSemantic proximity Read ↗

Age-Related Changes in the Inflammatory Status of Human Mesenchymal Stem Cells: Implications for Cell TherapySemantic proximity Read ↗

Stem Cells as Vehicles for Youthful Regeneration of Aged TissuesSemantic proximity Read ↗

Mechanisms and therapeutic strategies linking mesenchymal stem cells senescence to osteoporosisSemantic proximity Read ↗

Microvesicles as Potential Biomarkers for the Identification of Senescence in Human Mesenchymal Stem CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.