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Article

Genomic retargeting of p53 and CTCF is associated with transcriptional changes during oncogenic HRas-induced transformation.

Communications biology - 25 Nov 2020

Schwartz Michal, Portugez Avital Sarusi, Attia Bracha Zukerman, Tannenbaum Miriam, Cohen Leslie, Loza Olga, Chase Emily, Turman Yousef, Kaplan Tommy, Salah Zaidoun, Hakim Ofir

Abstract excerpt

Gene transcription is regulated by distant regulatory elements via combinatorial binding of transcription factors. It is increasingly recognized that alterations in chromatin state and transcription factor binding in these distant regulatory elements may have key roles in cancer development. Here we focused on the first stages of oncogene-induced carcinogenic transformation, and characterized the regulatory...

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Identifiers

PMID: 33239721
DOI: 10.1038/s42003-020-01398-y
PMCID: PMC7809021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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