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Targeting Chromatin-Remodeling Factors in Cancer Cells: Promising Molecules in Cancer Therapy

24 Oct 2022

Abstract excerpt

ATP-dependent chromatin-remodeling complexes can reorganize and remodel chromatin and thereby act as important regulator in various cellular processes. Based on considerable studies over the past two decades, it has been confirmed that the abnormal function of chromatin remodeling plays a pivotal role in genome reprogramming for oncogenesis in cancer development and/or resistance to cancer therapy. Recently,...

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PMID: 36361605
DOI: 10.3390/ijms232112815

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