Article

Distinct oncogenes drive distinct genome and epigenome alterations in human mammary epithelial cells

2018-06-11

Abstract excerpt

Gene expression differences, combined with distinct patterns of genomic rearrangements and epigenetic modifications, have laid the bases of molecular classification of breast cancer. Different molecular subtypes are thought to originate from different cell lineages in the mammary gland, but the early activation of an oncogene could also play a role. It is, however, difficult to discriminate the respective inputs o...

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Literature Corpus work: 75b47306-30f5-5d3a-b048-b7d9047cd86a
DOI: 10.1101/344465

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