Article
Assessing Genetic Overlap Between Platelet Parameters and Neurodegenerative Disorders.
Frontiers in immunology - 1 Jan 2020
Tirozzi Alfonsina, Izzi Benedetta, Noro Fabrizia, Marotta Annalisa, Gianfagna Francesco, Hoylaerts Marc F, Cerletti Chiara, Donati Maria Benedetta, de Gaetano Giovanni, Iacoviello Licia, Gialluisi Alessandro
Abstract excerpt
Neurodegenerative disorders such as Parkinson's disease (PD) and Alzheimer's disease (AD) suffer from the lack of risk-predictive circulating biomarkers, and clinical diagnosis occurs only when symptoms are evident. Among potential biomarkers, platelet parameters have been associated with both disorders. However, these associations have been scarcely investigated at the genetic level. Here, we tested genome-wide...
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