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Article

Correlation analysis of peripheral platelet markers and disease phenotypes in Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Jun 2024

Fu Jiajia, Lai Xiaohui, Zhang Chongwei, Wei Qianqian, Chen Xueping, Shang Huifang

Abstract excerpt

INTRODUCTION: Platelets serve as the primary peripheral reservoir of amyloid beta (Aβ). However, there is limited research on platelet markers in routine blood examinations, particularly with regard to the large platelet ratio (P-LCR) in Alzheimer's disease (AD). METHODS: This study included 512 AD patients and 205 healthy controls (HCs). Platelet markers and apolipoprotein E (APOE) 4 status were assessed in all...

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Identifiers

PMID: 38713702
DOI: 10.1002/alz.13841
PMCID: PMC11180931

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