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Article

Polygenic Risk Scores in Neurodegenerative Diseases: a Review

2019-01-17

Abstract excerpt

This review summarizes the current state of the art of polygenic risk scores (PRSs) in the assessment of risk for neurodegenerative diseases. Polygenic risk scores have been used to identify the shared genetic architecture between comorbid complex traits, disease presentations, and disease endophenotypes. The pathological and symptomatologic overlap between neurodegenerative diseases is strikingly high. In some ca...

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Literature Corpus work
6af70390-7705-57c6-a01c-817c9d33fc61
DOI
10.1007/s40142-019-0158-0
Open publication

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Polygenic Risk Scores in Neurodegenerative Diseases: a ReviewDOI 10.1007/s40142-019-0158-0
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