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Article

Metabolic Coordination of Cell Fate by α-Ketoglutarate-Dependent Dioxygenases.

Trends in cell biology - 1 Jan 2021

Baksh Sanjeethan C, Finley Lydia W S

Abstract excerpt

Cell fate determination requires faithful execution of gene expression programs, which are increasingly recognized to respond to metabolic inputs. In particular, the family of α-ketoglutarate (αKG)-dependent dioxygenases, which include several chromatin-modifying enzymes, are emerging as key mediators of metabolic control of cell fate. αKG-dependent dioxygenases consume the metabolite αKG (also known as...

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Identifiers

PMID: 33092942
DOI: 10.1016/j.tcb.2020.09.010
PMCID: PMC7748998

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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