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Article

Metabolic rewiring underpins human trophoblast induction

2024-03-19

Abstract excerpt

<title>Abstract</title> <p>Development is driven by a sequence of molecularly interconnected transcriptional, epigenetic, and metabolic changes. Specific metabolites, like α-ketoglutarate (αKG), function as signalling molecules affecting the activity of chromatin modifying enzymes. It remains unclear, how such non-canonical function of metabolism coordinates specific cell-state changes especially in early develop...

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Literature Corpus work
d54c0bb6-22cd-5a07-8c36-04b1eacea5dd
DOI
10.21203/rs.3.rs-3575549/v1
Open publication

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Metabolic rewiring underpins human trophoblast inductionDOI 10.21203/rs.3.rs-3575549/v1
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