Genetically predicted telomere length is associated with clonal somatic copy number alterations in peripheral leukocytes

Abstract excerpt

Telomeres are DNA-protein structures at the ends of chromosomes essential in maintaining chromosomal stability. Observational studies have identified associations between telomeres and elevated cancer risk, including hematologic malignancies; but biologic mechanisms relating telomere length to cancer etiology remain unclear. Our study sought to better understand the relationship between telomere length and cancer...

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• Share to Epigenetics and DNA Methylation
• Share to Genomic variations and chromosomal abnormalities
• Share to Telomeres, Telomerase, and Senescence