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Determinants of chromosome-specific telomere lengths among 2,573 All of Us participants

2025-08-18

Abstract excerpt

<title>Abstract</title> <p>Telomeres are DNA-protein structures that protect chromosome ends. The DNA component of telomeres shortens as cells divide, and telomere length (TL) is a key biomarker of aging and disease risk. Most previous studies in humans of TL have analyzed average TL; thus, our knowledge of TL variability across chromosome arms remains limited. The availability of long-read whole-genome sequencin...

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Literature Corpus work
693d1380-47bb-55d1-9edc-1f7bf9bb190a
DOI
10.21203/rs.3.rs-7293781/v1
Open publication

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