Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cancer Plasticity: The Role of mRNA Translation.

Trends in cancer - 1 Feb 2021

Lee Laura J, Papadopoli David, Jewer Michael, Del Rincon Sonia, Topisirovic Ivan, Lawrence Mitchell G, Postovit Lynne-Marie

Abstract excerpt

Tumor progression is associated with dedifferentiated histopathologies concomitant with cancer cell survival within a changing, and often hostile, tumor microenvironment. These processes are enabled by cellular plasticity, whereby intracellular cues and extracellular signals are integrated to enable rapid shifts in cancer cell phenotypes. Cancer cell plasticity, at least in part, fuels tumor heterogeneity and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Plasticity
Share to Drug Resistance, Neoplasm
Share to Epithelial-Mesenchymal Transition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Eukaryotic Initiation Factor-2

Share to Genetic Heterogeneity

Share to Oxidative Phosphorylation

Share to Protein Biosynthesis

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 33067172
DOI: 10.1016/j.trecan.2020.09.005
PMCID: PMC8023421

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cancer Plasticity: The Role of mRNA Translation.PMID 33067172Read ↗

Epigenetic regulation of mRNA mediates the phenotypic plasticity of cancer cells during metastasis and therapeutic resistance (Review).Semantic proximity Read ↗

Translational control in cancer etiology.Semantic proximity Read ↗

Translational Regulation of Cancer Metastasis.Semantic proximity Read ↗

The cancerous translation apparatus.Semantic proximity Read ↗

Translational control of aberrant stress responses as a hallmark of cancer.Semantic proximity Read ↗

Translational control of breast cancer plasticitySemantic proximity Read ↗

Hyperacute Response Proteins (HARPs) synthesized on γ-tubulin-FTO-MARK4 translation microdomains upon exposure to stress, regulate stress response in cancerSemantic proximity Read ↗

Mechanisms of translational deregulation in human tumors and therapeutic intervention strategies.Semantic proximity Read ↗

The molecular determinants of phenotypic plasticity in homeostasis and neoplasiaSemantic proximity Read ↗

ALKBH1 drives codon-biased, pro-oncogenic translation and tumor microenvironment remodeling in glioma via tRNA wobble oxidationSemantic proximity Read ↗

Translation initiation in cancer: a novel target for therapy.Semantic proximity Read ↗

The pathogenesis of mesothelioma is driven by a dysregulated translatomeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.