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Article

Mechanisms of translational deregulation in human tumors and therapeutic intervention strategies.

Oncogene - 6 Sept 2007

Bilanges B, Stokoe D

Abstract excerpt

Analysis of the recurrent genetic aberrations present in human tumors provides insight into how normal cells escape appropriate proliferation and survival cues. Commonly mutated genes encode proteins that monitor DNA damage (e.g., p53), proteins that regulate the cell cycle (such as Rb), and prot...

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Source

Identifiers

PMID: 17404576
DOI: 10.1038/sj.onc.1210431

Genes

APC
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17404576-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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