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Article

Epigenetic regulation of mRNA mediates the phenotypic plasticity of cancer cells during metastasis and therapeutic resistance (Review).

Oncology reports - 1 Feb 2024

Zhang Chunzhi, Liang Siyuan, Zhang Hanning, Wang Ruoxi, Qiao Huanhuan

Abstract excerpt

Plasticity, the ability of cancer cells to transition between differentiation states without genomic alterations, has been recognized as a major source of intratumoral heterogeneity. It has a crucial role in cancer metastasis and treatment resistance. Thus, targeting plasticity holds tremendous promise. However, the molecular mechanisms of plasticity in cancer cells remain poorly understood. Several studies found...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

Share to Epigenesis, Genetic

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Share to RNA, Long Noncoding

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Source

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Identifiers

PMID: 38131215
DOI: 10.3892/or.2023.8687
PMCID: PMC10777459

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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