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Article

Comprehensive genetic features of gastric mixed adenoneuroendocrine carcinomas and pure neuroendocrine carcinomas.

The Journal of pathology - 1 Jan 2021

Koh Jiwon, Nam Soo Kyung, Kwak Yoonjin, Kim Gilhyang, Kim Ka-Kyung, Lee Byung-Chul, Ahn Sang-Hoon, Park Do Joong, Kim Hyung-Ho, Park Kyoung Un, Kim Woo Ho, Lee Hye Seung

Abstract excerpt

We aimed to determine the pathogenesis of gastric mixed adenoneuroendocrine carcinoma (MANEC) and pure neuroendocrine carcinoma (NEC), which is largely unknown. Targeted DNA sequencing was performed on 34 tumor samples from 21 patients - 13 adenocarcinoma (ADC)/NEC components from MANECs and eight pure NECs - and 21 matched non-neoplastic gastric tissues. Mutational profiles of MANECs/NECs were compared with...

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Identifiers

PMID: 32985687
DOI: 10.1002/path.5556

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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