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Article

Distinctive Phenotypic and Microenvironmental Characteristics of Neuroendocrine Carcinoma and Adenocarcinoma Components in Gastric Mixed Adenoneuroendocrine Carcinoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Oct 2024

Kwak Yoonjin, Nam Soo Kyung, Park Yujun, Suh Yun-Suhk, Ahn Sang-Hoon, Kong Seong-Ho, Park Do Joong, Lee Hyuk-Joon, Kim Hyung-Ho, Yang Han-Kwang, Lee Hye Seung

Abstract excerpt

This study aimed to conduct an in-depth examination of gene expression and microenvironmental profiles of gastric neuroendocrine carcinoma (NEC) and mixed adeno-NEC (MANEC). Tissue microarrays from 55 patients with gastric MANEC (N = 32) or NEC (N = 23) were analyzed using digital spatial profiling (GeoMx DSP, NanoString Technologies). Representative regions of interest were selected from the adenocarcinoma (ADC)...

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Source

Identifiers

PMID: 39029904
DOI: 10.1016/j.modpat.2024.100568

Genes

DSP
AKT3
BGN
COL1A1
FN1
MAP1B
PEG10
SPARC
STMN3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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