Article
Molecular profiling of gastric neuroendocrine carcinomas.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Sept 2023
Ikegame Ko, Hatakeyama Keiichi, Terashima Masanori, Sugino Takashi, Aizawa Daisuke, Furukawa Kenichiro, Fujiya Keiichi, Tanizawa Yutaka, Bando Etsuro, Yamaguchi Ken
Abstract excerpt
Gastric neuroendocrine carcinoma (G-NEC) usually has NEC and adenocarcinoma components and is considered to have a common origin in gastric adenocarcinoma because common pathogenic mutations are shared. However, G-NEC without adenocarcinoma also exists, and it may have a different mechanism of tumorigenesis. We aimed to elucidate the tumorigenesis of G-NEC by focusing on the proportion of NEC components. Thirteen...
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