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Article

Colorectal mixed adenoneuroendocrine carcinomas and neuroendocrine carcinomas are genetically closely related to colorectal adenocarcinomas.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Apr 2017

Jesinghaus Moritz, Konukiewitz Björn, Keller Gisela, Kloor Matthias, Steiger Katja, Reiche Magdalena, Penzel Roland, Endris Volker, Arsenic Ruza, Hermann Gratiana, Stenzinger Albrecht, Weichert Wilko, Pfarr Nicole, Klöppel Günter

Abstract excerpt

Colorectal mixed adenoneuroendocrine carcinomas are rare and clinically aggressive neoplasms with considerable morphological heterogeneity. Data on their genomic characteristics and molecular associations to either conventional colorectal adenocarcinomas or poorly differentiated neuroendocrine neoplasms is still scarce, hampering optimized patient treatment and care. Tissue from 19 colorectal mixed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28059096
DOI: 10.1038/modpathol.2016.220

Genes

APC
BRAF
KRAS
RET

Provenance

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