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Article

The transport pathway in the ABCG2 protein and its regulation revealed by molecular dynamics simulations.

Cellular and molecular life sciences : CMLS - 1 Mar 2021

Nagy Tamás, Tóth Ágota, Telbisz Ágnes, Sarkadi Balázs, Tordai Hedvig, Tordai Attila, Hegedűs Tamás

Abstract excerpt

Atomic-level structural insight on the human ABCG2 membrane protein, a pharmacologically important transporter, has been recently revealed by several key papers. In spite of the wealth of structural data, the pathway of transmembrane movement for the large variety of structurally different ABCG2 substrates and the physiological lipid regulation of the transporter has not been elucidated. The complex molecular...

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32979053
DOI: 10.1007/s00018-020-03651-3
PMCID: PMC7966132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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