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Article

Three pleiotropic loci associated with bone mineral density and lean body mass.

Molecular genetics and genomics : MGG - 1 Jan 2021

Zhang Yu-Xue, Zhang Shan-Shan, Ran Shu, Liu Yu, Zhang Hong, Yang Xiao-Lin, Hai Rong, Shen Hui, Tian Qing, Deng Hong-Wen, Zhang Lei, Pei Yu-Fang

Abstract excerpt

Both bone mineral density (BMD) and lean body mass (LBM) are important physiological measures with strong genetic determination. Besides, BMD and LBM might have common genetic factors. Aiming to identify pleiotropic genomic loci underlying BMD and LBM, we performed bivariate genome-wide association study meta-analyses of femoral neck bone mineral density and LBM at arms and legs, and replicated in the large-scale...

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Identifiers

PMID: 32970232
DOI: 10.1007/s00438-020-01724-3
PMCID: PMC7903521

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