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Article

Twelve New Genomic Loci Associated With Bone Mineral Density.

Frontiers in endocrinology - 1 Jan 2020

Liu Lu, Zhao Min, Xie Zong-Gang, Liu Ju, Peng Hui-Ping, Pei Yu-Fang, Sun Hong-Peng, Zhang Lei

Abstract excerpt

Aiming to identify more genomic loci associated with bone mineral density (BMD), we conducted a joint association analysis of 2 genome-wide association study (GWAS) by the integrative association method multi-trait analysis of GWAS (MTAG). The first one is the single GWAS of estimated heel BMD (eBMD) in the UK biobank (UKB) cohort (N = 426,824), and the second one is the GWAS meta-analysis of total body BMD...

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Biomarkers
Bone Density
Follow-Up Studies
Genome-Wide Association Study
Genomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Quantitative Trait Loci

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PMID: 32390946
DOI: 10.3389/fendo.2020.00243
PMCID: PMC7188784

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