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Article

Two functional variants at 6p21.1 were associated with lean mass.

Skeletal muscle - 23 Nov 2019

Pei Yu-Fang, Hu Wen-Zhu, Yang Xiao-Lin, Wei Xin-Tong, Feng Gui-Juan, Zhang Hong, Shen Hui, Tian Qing, Deng Hong-Wen, Zhang Lei

Abstract excerpt

BACKGROUND: Low lean body mass is the most important predictor of sarcopenia with strong genetic background. The aim of this study was to uncover genetic factors underlying lean mass development. MATERIALS AND METHODS: We performed a genome-wide association study (GWAS) of fat-adjusted leg lean mass in the Framingham Heart Study (FHS, N = 6587), and replicated in the Women's Health Initiative-African American...

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Identifiers

PMID: 31757224
DOI: 10.1186/s13395-019-0212-3
PMCID: PMC6874818

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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