Article
Four pleiotropic loci associated with fat mass and lean mass.
International journal of obesity (2005) - 1 Oct 2020
Liu Yu, Ran Shu, Lin Yong, Zhang Yu-Xue, Yang Xiao-Lin, Wei Xin-Tong, Jiang Zi-Xuan, He Xiao, Zhang Hong, Feng Gui-Juan, Shen Hui, Tian Qing, Deng Hong-Wen, Zhang Lei, Pei Yu-Fang
Abstract excerpt
BACKGROUND: Fat mass and lean mass are two biggest components of body mass. Both fat mass and lean mass are under strong genetic determinants and are correlated. METHODS: We performed a bivariate genome-wide association meta-analysis of (lean adjusted) leg fat mass and (fat adjusted) leg lean mass in 12,517 subjects from 6 samples, and followed by in silico replication in large-scale UK biobank cohort sample...
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