Article
A bivariate whole-genome linkage scan suggests several shared genomic regions for obesity and osteoporosis.
The Journal of clinical endocrinology and metabolism - 1 Jul 2007
Tang Zi-Hui, Xiao Peng, Lei Shu-Feng, Deng Fei-Yan, Zhao Lan-Juan, Deng Hong-Yi, Tan Li-Jun, Shen Hui, Xiong Dong-Hai, Recker Robert R, Deng Hong-Wen
Abstract excerpt
CONTEXT: A genome-wide bivariate analysis was conducted for body fat mass (BFM) and bone mineral density (BMD) in a large Caucasian sample. We found some quantitative trait loci shared by BFM and BMD in the total sample and the gender-specific subgroups, and quantitative trait loci with potential pleiotropy were disclosed. BFM and BMD, as the respective measure for obesity and osteoporosis, are phenotypically and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
