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Article

Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.

Bone - 1 May 2018

Pei Yu-Fang, Hu Wen-Zhu, Yan Min-Wei, Li Chang-Wei, Liu Lu, Yang Xiao-Lin, Hai Rong, Wang Xiu-Yan, Shen Hui, Tian Qing, Deng Hong-Wen, Zhang Lei

Abstract excerpt

In the present study, aiming to identify loci associated with osteoporosis, we conducted a joint association study of 2 independent genome-wide association meta-analyses of femoral neck and lumbar spine bone mineral densities (BMDs): 1) an in-house study of 6 samples involving 7484 subjects, and 2) the GEFOS-seq study of 7 samples involving 32,965 subjects. The in-house samples were imputed by the 1000 genomes...

Topics

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Bone Density
Chromosomes, Human, Pair 12
Chromosomes, Human, Pair 13
Genetic Associations and Epidemiology
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genome-Wide Association Study

Polymorphism, Single Nucleotide

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Open in PubMed Open full text

Identifiers

PMID: 29499414
DOI: 10.1016/j.bone.2018.02.027
PMCID: PMC6329308

Genes

MACROD2
OSBPL2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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