Article
HLA-DRB1 Alleles are Associated With COPD in a Latin American Admixed Population.
Archivos de bronconeumologia - 1 Apr 2021
Díaz-Peña Roberto, Silva Rafael S, Hosgood H Dean, Jaime Sergio, Miravitlles Marc, Olloquequi Jordi
Abstract excerpt
INTRODUCTION: While the molecular mechanisms of COPD pathogenesis remain obscure, there is mounting evidence supporting a key role for autoimmunity. Although human leukocyte antigens (HLA) alleles have been repeatedly associated with autoimmune processes, the relation between HLA and COPD remains largely unexplored, especially in Latin American (LA) populations. Consequently, this study aimed to investigate the...
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