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Article

Alleles of HLA-DRB1*04 Associated with Pulmonary Tuberculosis in Amazon Brazilian Population.

PloS one - 1 Jan 2016

Souza de Lima Dhêmerson, Morishi Ogusku Mauricio, Porto Dos Santos Maisa, de Melo Silva Cláudia Maria, Alves de Almeida Vanessa, Assumpção Antunes Irineide, Boechat Antonio Luiz, Ramasawmy Rajendranath, Sadahiro Aya

Abstract excerpt

Immunogenetic host factors are associated with susceptibility or protection to tuberculosis (TB). Strong associations of HLA class II genes with TB are reported. We analyzed the HLA-DRB1*04 alleles to identify subtypes associated with pulmonary TB and their interaction with risk factors such as alcohol, smoking, and gender in 316 pulmonary TB patients and 306 healthy individuals from the Brazilian Amazon. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to HLA-DRB1 Chains

Share to Immune Cell Function and Interaction

Share to Polymorphism, Genetic

Share to Tuberculosis, Pulmonary

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Identifiers

PMID: 26901036
DOI: 10.1371/journal.pone.0147543
PMCID: PMC4764689

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