Article
Description and first insights on a large genomic biobank of lung transplantation.
European journal of human genetics : EJHG - 1 Mar 2025
Brocard Simon, Morin Martin, Dos Santos Brito Silva Nayane, Renaud-Picard Benjamin, Coiffard Benjamin, Demant Xavier, Falque Loïc, Le Pavec Jérome, Roux Antoine, Villeneuve Thomas, Knoop Christiane, Mornex Jean-François, Salpin Mathilde, Boussaud Véronique, Rousseau Olivia, Mauduit Vincent, Durand Axelle, Magnan Antoine, Gourraud Pierre-Antoine, Vince Nicolas, Südholt Mario, Tissot Adrien, Limou Sophie
Abstract excerpt
The main limitation to long-term lung transplant (LT) survival is chronic lung allograft dysfunction (CLAD), which leads to irreversible lung damage and significant mortality. Individual factors can impact CLAD, but no large genetic investigation has been conducted to date. We established the multicentric Genetic COhort in Lung Transplantation (GenCOLT) biobank from a rich and homogeneous sub-part of COLT cohort....
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