Article

Genome-wide association study reveals two novel genetic loci associated with chronic lung allograft dysfunction

2025-11-07

Abstract excerpt

<h4>Background</h4> Chronic lung allograft dysfunction (CLAD) leads to declining respiratory function and high mortality, representing the main barrier to long-term survival in lung transplantation (LT). We performed the first genome-wide association study (GWAS) investigating donor’s and recipient’s genetic factors associated with CLAD. <h4>Method</h4> We genotyped 392 donor-recipient pairs from the multicentri...

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Literature Corpus work: 6c0bc17e-0ce9-5d74-a026-cbbebc782ca2
DOI: 10.1101/2025.11.05.25339596

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