Description and first insights on a large genomic biobank of lung transplantation

Abstract excerpt

<title>Abstract</title> <p>The main limitation to long-term lung transplant (LT) survival is chronic lung allograft dysfunction (CLAD), which leads to irreversible lung damage and significant mortality. Individual factors can impact CLAD, but no large genetic investigation has been conducted to date. We established the multicentric Genetic COhort in Lung Transplantation (GenCOLT) biobank upon the rich and homogen...

Topics

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• Allografts
• Biological Specimen Banks
• Chronic Disease
• Genome-Wide Association Study
• HLA Antigens
• Lung Transplantation
• Polymorphism, Single Nucleotide
• Tissue Donors

Identifiers and source

Literature Corpus work

3c0b7363-ddc6-50c6-9fba-54d409dfe84d

DOI

10.21203/rs.3.rs-3999519/v1