Article

Fast Low-Input Efficient Hi-C

2024-08-29

Abstract excerpt

We developed FLIE (Fast Low-Input Efficient) Hi-C, a highly optimized and simplified version of Hi-C. Our method shortens the duration of Hi-C from five days to two days and decreases key reagent amounts 5-20 fold, while maintaining experimental controls and data quality. Importantly, the method also reduces the required input material by 100-1000 fold, as we demonstrate by generating detailed high complexity inte...

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Literature Corpus work: ddadeeea-3249-5c51-82e2-f26821132561
DOI: 10.1101/2024.08.28.609956

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