Article

A Genome-wide Library of MADM Mice for Single-Cell Genetic Mosaic Analysis

2020-06-06

Abstract excerpt

<h4>SUMMARY</h4> Mosaic Analysis with Double Markers (MADM) offers a unique approach to visualize and concomitantly manipulate genetically-defined cells in mice with single-cell resolution. MADM applications include the analysis of lineage; single-cell morphology and physiology; genomic imprinting phenotypes; and dissection of cell-autonomous gene functions in vivo in health and disease. Yet, MADM could only be...

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Literature Corpus work: 56b3b9ce-512c-51f8-a727-de45ba2153d8
DOI: 10.1101/2020.06.05.136192

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