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Article

CD4 T Follicular Helper Cells Prevent Depletion of Follicular B Cells in Response to Cecal Ligation and Puncture.

Frontiers in immunology - 1 Jan 2020

Taylor Matthew D, Brewer Mariana R, Nedeljkovic-Kurepa Ana, Yang Yihe, Reddy Kalpana S, Abraham Mabel N, Barnes Betsy J, Deutschman Clifford S

Abstract excerpt

Recent studies have demonstrated that induction of a diverse repertoire of memory T cells ("immune education") affects responses to murine cecal ligation and puncture (CLP), the most widely - used animal model of sepsis. Among the documented effects of immune education on CLP are changes in T cell, macrophage and neutrophil activity, more pronounced organ dysfunction and reduced survival. Little is known,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32903485
DOI: 10.3389/fimmu.2020.01946
PMCID: PMC7434988

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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