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Article

An exaggerated inflammatory response after CLP correlates with a negative outcome.

The Journal of surgical research - 1 May 2005

Torres Manuel B, De Maio Antonio

Abstract excerpt

BACKGROUND: Sepsis is the leading cause of morbidity and mortality in the surgical intensive care unit. We postulate that the variable clinical profile of septic patients is the product of multiple factors, including initiating insult, environment, and genetic make-up. This hypothesis was tested by changing the severity of the insult and the genetic background in an experimental murine model of sepsis. MATERIALS...

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PMID: 15836855
DOI: 10.1016/j.jss.2004.11.025

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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