Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased attrition of memory T cells during sepsis requires 2B4

1 May 2019

Abstract excerpt

Recent seminal studies have revealed that laboratory mice differ from adult humans with regard to the frequency, number, and distribution of memory T cells. Because our data show that memory T cells are more susceptible to sepsis-induced death than naive T cells, in this study we developed a model in which mice possess a memory T cell compartment more similar to that of adult humans, to better study immune...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Cell Function and Interaction
Share to Immune Response and Inflammation
Share to Sepsis Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31045575
DOI: 10.1172/jci.insight.126030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased attrition of memory T cells during sepsis requires 2B4PMID 31045575Read ↗

Sepsis leads to lasting changes in phenotype and function of memory CD8 T cells.Semantic proximity Read ↗

Sepsis leads to lasting changes in phenotype and function of naïve CD8 T cells.Semantic proximity Read ↗

Splenic CD4+ T cells have a distinct transcriptional response six hours after the onset of sepsis.Semantic proximity Read ↗

Tumor-Specific T Cells Exacerbate Mortality and Immune Dysregulation during Sepsis.Semantic proximity Read ↗

Septic Shock Shapes B Cell Response toward an Exhausted-like/Immunoregulatory Profile in PatientsSemantic proximity Read ↗

Impact of sepsis on CD4 T cell immunity.Semantic proximity Read ↗

Polymicrobial sepsis impairs bystander recruitment of effector cells to infected skin despite optimal sensing and alarming function of skin resident memory CD8 T cellsSemantic proximity Read ↗

BTLA expression contributes to septic morbidity and mortality by inducing innate inflammatory cell dysfunction.Semantic proximity Read ↗

The Autoimmune Risk R262W Variant of the Adaptor SH2B3 Improves Survival in Sepsis.Semantic proximity Read ↗

Impaired B-Cell Maturation Contributes to Reduced B Cell Numbers and Poor Prognosis in SepsisSemantic proximity Read ↗

Lymphocytes, apoptosis and sepsis: making the jump from mice to humansSemantic proximity Read ↗

A prospective analysis of lymphocyte phenotype and function over the course of acute sepsis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.