Article
Endotoxic shock-expanded murine CD11c low CD45RB + regulatory dendritic cells modulate inflammatory T cell responses through multiple mechanisms.
Scientific reports - 29 May 2015
Wang Xiaoqian, Wang Qingyang, Zhang Xueying, Li Yajing, Wang Jingyang, Hou Chunmei, Chen Juan, Shen Beifen, Shi Yanchun, Zhang Jiyan
Abstract excerpt
Changes in the number and function of dendritic cells (DCs) have been reported to play an important role in endotoxin tolerance. It has been reported that expansion of splenic CD11c(low)CD45RB(+) DCs occurs in mice injected with sublethal doses of lipopolysaccharide (LPS). However, the function of endotoxic shock-expanded CD11c(low)CD45RB(+) DCs has not been examined. In this work, we show that endotoxic shock...
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