Article
Genomic Regions 10q22.2, 17q21.31, and 2p23.1 Can Contribute to a Lower Lung Function in African Descent Populations.
Genes - 4 Sept 2020
Fonseca Héllen, da Silva Thiago M, Saraiva Mariana, Santolalla Meddly L, Sant'Anna Hanaisa P, Araujo Nathalia M, Lima Natália P, Rios Raimon, Tarazona-Santos Eduardo, Horta Bernardo L, Cruz Alvaro, Barreto Mauricio L, Figueiredo Camila A
Abstract excerpt
Accumulated evidence supports the contribution of genetic factors in modulating airway function, especially ancestry. We investigated whether genetic polymorphisms can affect lung function in a mixed Brazilian child population using the admixture mapping strategy through RFMix software version 1.5.4 (Stanford University, Stanford, CA, USA), followed by fine mapping, to identify regions whereby local African or...
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