Article
Case-control admixture mapping in Latino populations enriches for known asthma-associated genes.
The Journal of allergy and clinical immunology - 1 Jul 2012
Torgerson Dara G, Gignoux Christopher R, Galanter Joshua M, Drake Katherine A, Roth Lindsey A, Eng Celeste, Huntsman Scott, Torres Raul, Avila Pedro C, Chapela Rocio, Ford Jean G, Rodríguez-Santana José R, Rodríguez-Cintrón William, Hernandez Ryan D, Burchard Esteban G
Abstract excerpt
BACKGROUND: Polymorphisms in more than 100 genes have been associated with asthma susceptibility, yet much of the heritability remains to be explained. Asthma disproportionately affects different racial and ethnic groups in the United States, suggesting that admixture mapping is a useful strategy to identify novel asthma-associated loci. OBJECTIVE: We sought to identify novel asthma-associated loci in Latino...
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