Article
Replication and fine mapping of asthma-associated loci in individuals of African ancestry.
Human genetics - 1 Sept 2013
Kantor David B, Palmer Cameron D, Young Taylor R, Meng Yan, Gajdos Zofia K, Lyon Helen, Price Alkes L, Pollack Samuela, London Stephanie J, Loehr Laura R, Smith Lewis J, Kumar Rajesh, Jacobs David R, Petrini Marcy F, O'Connor George T, White Wendy B, Papanicolaou George, Burkart Kristin M, Heckbert Susan R, Barr R Graham, Hirschhorn Joel N
Abstract excerpt
Asthma originates from genetic and environmental factors with about half the risk of disease attributable to heritable causes. Genome-wide association studies, mostly in populations of European ancestry, have identified numerous asthma-associated single nucleotide polymorphisms (SNPs). Studies in populations with diverse ancestries allow both for identification of robust associations that replicate across ethnic...
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