Article
Genetic ancestry influences asthma susceptibility and lung function among Latinos.
The Journal of allergy and clinical immunology - 1 Jan 2015
Pino-Yanes Maria, Thakur Neeta, Gignoux Christopher R, Galanter Joshua M, Roth Lindsey A, Eng Celeste, Nishimura Katherine K, Oh Sam S, Vora Hita, Huntsman Scott, Nguyen Elizabeth A, Hu Donglei, Drake Katherine A, Conti David V, Moreno-Estrada Andres, Sandoval Karla, Winkler Cheryl A, Borrell Luisa N, Lurmann Fred, Islam Talat S, Davis Adam, Farber Harold J, Meade Kelley, Avila Pedro C, Serebrisky Denise, Bibbins-Domingo Kirsten, Lenoir Michael A, Ford Jean G, Brigino-Buenaventura Emerita, Rodriguez-Cintron William, Thyne Shannon M, Sen Saunak, Rodriguez-Santana Jose R, Bustamante Carlos D, Williams L Keoki, Gilliland Frank D, Gauderman W James, Kumar Rajesh, Torgerson Dara G, Burchard Esteban G
Abstract excerpt
BACKGROUND: Childhood asthma prevalence and morbidity varies among Latinos in the United States, with Puerto Ricans having the highest and Mexicans the lowest. OBJECTIVE: To determine whether genetic ancestry is associated with the odds of asthma among Latinos, and secondarily whether genetic ancestry is associated with lung function among Latino children. METHODS: We analyzed 5493 Latinos with and without asthma...
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