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Article

Integrative genomic analysis in African American children with asthma finds three novel loci associated with lung function.

Genetic epidemiology - 1 Mar 2021

Goddard Pagé C, Keys Kevin L, Mak Angel C Y, Lee Eunice Y, Liu Amy K, Samedy-Bates Lesly-Anne, Risse-Adams Oona, Contreras María G, Elhawary Jennifer R, Hu Donglei, Huntsman Scott, Oh Sam S, Salazar Sandra, Eng Celeste, Himes Blanca E, White Marquitta J, Burchard Esteban G

Abstract excerpt

Bronchodilator (BD) drugs are commonly prescribed for treatment and management of obstructive lung function present with diseases such as asthma. Administration of BD medication can partially or fully restore lung function as measured by pulmonary function tests. The genetics of baseline lung function measures taken before BD medication have been extensively studied, and the genetics of the BD response itself...

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Identifiers

PMID: 32989782
DOI: 10.1002/gepi.22365
PMCID: PMC7902343

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