Article
ARMS TaqMan real-time PCR for genotyping factor V Leiden mutation in Han Chinese.
Electrophoresis - 1 Dec 2020
Yu Pan, Dai Yibei, Dong Jiantao, Zhang Luyan, Ping Ying, Wang Xuchu, Wang Danhua, Tao Zhihua
Abstract excerpt
Factor V Leiden (FVLeiden ) is a missense mutation of 1691 position (G1691A) in exon 10 of FV gene, and being a genetic risk for venous thrombosis. Currently, there are several PCR-based methods for detecting FVLeiden mutation; however, these methods have disadvantages such as time-consuming, cumbersome steps and potentially hazardous gels. The aims of present study were to develop a simple, time-saving,...
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