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Article

ARMS test for diagnosis of factor VLeiden mutation, a common cause of inherited thrombotic tendency.

Journal of clinical laboratory analysis - 1 Jan 1996

Yandava C N, Zappulla D C, Korf B R, Neufeld E J

Abstract excerpt

We developed a simple and rapid amplification-refractory mutation system (ARMS) assay for the factor V mutation [R506Q] (factor VLeiden), which results in the autosomal dominant thrombotic tendency, resistance to activated protein C (rAPC). PCR primers within Exon 10 of the factor V gene were designed. A common upstream primer was paired with either a mutant or wild-type-specific downstream primer. The 3'-most...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8951612
DOI: 10.1002/(SICI)1098-2825(1996)10:6<414::AID-JCLA17>3.0.CO;2-#

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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