Testing for Factor V Leiden (FVL) and Prothrombin G20210A Genetic Variants.

doi:10.1007/978-1-0716-3175-1_14

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Article

Testing for Factor V Leiden (FVL) and Prothrombin G20210A Genetic Variants.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2023

Pajič Tadej

Abstract excerpt

Laboratory testing for Factor V Leiden and Prothrombin G20210A genetic variants permits defining the increased relative risk for venous thromboembolism in selected patients. Laboratory DNA testing for these variants may be undertaken by a variety of methods, including fluorescence-based quantitative real-time PCR (qPCR). This is a rapid, simple, robust, and reliable method to identify genotypes of interest. This...

Topics

Risk Factors
Prothrombin
Mutation
Humans
Thrombophilia
Genotype
Real-Time Polymerase Chain Reaction
Factor V
Venous Thromboembolism

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PMID: 37204714
DOI: 10.1007/978-1-0716-3175-1_14

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