ARMS test for diagnosis of CYP2C9 and VKORC1 mutation in patients with pulmonary embolism in Han Chinese.

doi:10.2217/pgs.09.138

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Article

ARMS test for diagnosis of CYP2C9 and VKORC1 mutation in patients with pulmonary embolism in Han Chinese.

Pharmacogenomics - 1 Jan 2010

Zhu Jin, Zhang Weijuan, Li Yanyan, Zhang Wei, Wang Heyao, Zheng Wenjie, Wang Chen

Abstract excerpt

AIMS: VKORC1 and CYP2C9 are important genetic factors affecting warfarin dose requirement. Our aim is to establish a simple, rapid and economical method to detect SNPs in the two genes. MATERIALS & METHODS: Primer Premier 5 was used and a normal primer, a mutational primer and a common primer have been designed using the amplification refractory mutation system for VKORC1 c.-1639G>A (rs9923231), CYP2C9*3...

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Identifiers

PMID: 20017677
DOI: 10.2217/pgs.09.138

Genes

VKORC1

Variants

rs9923231
rs1057910

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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